Coming October 1, 2026: 2026Q4 HCPCS Level II changes

2026Q4 takes effect on October 1, 2026. Until then 2026Q3 is the current release, and every code page on this site shows 2026Q3. This list is generated from the official release files: 45 codes added, 17 changed, 15 deleted.

Added codes (45)

• A2046 Dermisphere hdrt, per square centimeter (add-on, list separately in addition to primary procedure)
• A2047 Lacertamatrix, per square centimeter (add-on, list separately in addition to primary procedure)
• A2048 Puraply mz, per milligram
• A2049 Theracor, per square centimeter (add-on, list separately in addition to primary procedure)
• A2050 Fibrillar collagen wound dressing, per milligram
• A4228 Supplies for maintenance of non-insulin, device-drug combination infusion catheter, per week
• A6614 Supplies and accessories for use with an external ocular negative pressure pump, any type, per month
• A9613 Piflufolastat f 18 (pylarify truvu), diagnostic, 1 millicurie
• C9311 Injection, eplontersen, 1 mg (code may be used for medicare when drug administered under the direct supervision of a physician, not for use when drug is self administered)
• C9312 Injection, trabectedin (apotex), not therapeutically equivalent to j9362, 0.01 mg
• C9313 Injection, pivekimab sunirine-pvzy, 0.01 mg
• E0788 Ambulatory infusion pump, specific device-drug combination, single or multiple channels, electric or battery operated, with administrative equipment, worn by patient
• E2403 External ocular negative pressure pump, electric
• G0685 Algorithm-based assessment of likelihood of autism spectrum disorder (asd), derived from validated analysis of eye-gaze data or other technology
• J0014 Cocaine hydrochloride nasal solution (goprelto), 1 mg
• J0643 Injection, leucovorin calcium, not otherwise specified, 1 mg
• J0644 Injection, leucovorin calcium (avyxa), 1 mg
• J0871 Injection, daptomycin (endo), not therapeutically equivalent to j0878, 1 mg
• J1757 Injection, tividenofusp alfa-eknm, 1 mg
• J1818 Injection, pegzilarginase-nbln, 0.05 mg
• J1946 Injection, furosemide (lasix onyu), 1 mg
• J1947 Injection, furosemide (furoscix), 1 mg
• J1957 Injection, levetiracetam, 5 mg
• J1958 Injection, levetiracetam in sodium chloride, 5 mg
• J3268 Injection, delafloxacin, 1 mg
• J3406 Injection, omidubicel-onlv, per therapeutic dose
• J7524 Mycophenolate mofetil, oral, 5 mg
• J7526 Injection, mycophenolate mofetil, 5 mg
• J7529 Mycophenolate mofetil, for suspension, oral, 5 mg
• J7530 Mycophenolate mofetil (myhibbin), oral suspension, 5 mg
• J7531 Prednisolone sodium phosphate, orally disintegrating tablet, 1 mg
• J9066 Injection, bendamustine hydrochloride (avyxa), 1 mg
• J9186 Injection, etoposide (avyxa), 1 mg
• J9187 Injection, etoposide, 1 mg
• J9191 Injection, fluorouracil (avyxa), 10 mg
• J9192 Injection, fluorouracil, 10 mg
• J9362 Injection, trabectedin, 0.01 mg
• L1330 Thoracic orthosis, sternal and/or sternocostal compression, may include anterior and/or posterior pads, panels, with or without frame, prefabricated, includes fitting and adjustment
• L1972 Ankle foot orthosis, plastic or other material with ankle joint, with or without dorsiflexion assist, prefabricated, off-the shelf
• L8697 External accessory for use with implantable phrenic nerve stimulation device, replacement, each
• Q4207 Carbon life, per square centimeter (add-on, list separately in addition to primary procedure)
• Q4223 Dermabind sl optic, per square centimeter (add-on, list separately in addition to primary procedure)
• Q4243 Amchomatrix, per square centimeter (add-on, list separately in addition to primary procedure)
• Q5172 Injection, filgrastim-laha (filkri), biosimilar, 1 microgram
• Q5173 Injection, denosumab-adet (ponlimsi), biosimilar, 1 mg

Revised codes (17)

• A2040 was: Microlyte painguard, per square centimeter
  now: Microlyte painguard (add-on, list separately in addition to primary procedure), per square centimeter
• A2041 was: Foundation drs+ duo, per square centimeter
  now: Foundation drs+ duo (add-on, list separately in addition to primary procedure), per square centimeter
• A2042 was: Foundation drs+ solo, per square centimeter
  now: Foundation drs+ solo (add-on, list separately in addition to primary procedure), per square centimeter
• A2043 was: Biobrane, per square centimeter
  now: Biobrane (add-on, list separately in addition to primary procedure), per square centimeter
• A2045 was: Novashield or novogen wound matrix, per square centimeter
  now: Novashield or novogen wound matrix (add-on, list separately in addition to primary procedure), per square centimeter
• A9595 was: Piflufolastat f-18, diagnostic, 1 millicurie
  now: Piflufolastat f 18 (pylarify), diagnostic, 1 millicurie
• C1982 was: Catheter, pressure-generating, (e.g., one-way valve, intermittently occlusive)
  now: Catheter, pressure-generating, (e.g., one-way valve or occlusion balloon, intermittently or temporarily occluding)
• C8004 was: Simulation angiogram with use of a pressure-generating catheter (e.g., one-way valve, intermittently occluding), inclusive of all radiological supervision and interpretation, intraprocedural roadmapping, and imaging guidance necessary to complete the angiogram, for subsequent therapeutic radioembolization of tumors
  now: Simulation angiogram with use of a pressure-generating catheter (e.g., one-way valve or occlusion balloon, intermittently or temporarily occluding), inclusive of all radiological supervision and interpretation, intraprocedural roadmapping, and imaging guidance necessary to complete the angiogram, for subsequent therapeutic radioembolization of tumors
• C9797 was: Vascular embolization or occlusion procedure with use of a pressure-generating catheter (e.g., one-way valve, intermittently occluding), inclusive of all radiological supervision and interpretation, intraprocedural roadmapping, and imaging guidance necessary to complete the intervention; for tumors, organ ischemia, or infarction
  now: Vascular embolization or occlusion procedure with use of a pressure-generating catheter (e.g., one-way valve or occlusion balloon, intermittently or temporarily occluding), inclusive of all radiological supervision and interpretation, intraprocedural roadmapping, and imaging guidance necessary to complete the intervention; for tumors, organ ischemia, or infarction
• C9812 was: Echogenic nerve block needles (e.g. sonoplex, sonoblock, sonotap), non-opioid medical device (must be a qualifying medicare non-opioid medical device for post-surgical pain relief in accordance with section 4135 of the caa, 2023)
  now: Echogenic and/or nerve stimulator-guided nerve block needles (e.g. SonoPlex, SonoBlock, SonoTap, Stimuplex), non-opioid medical device (must be a qualifying Medicare non-opioid medical device for post-surgical pain relief in accordance with Section 4135 of the CAA, 2023)
• J3300 was: Injection, triamcinolone acetonide, preservative free, 1 mg
  now: Injection, triamcinolone acetonide (triesence), preservative free, 1 mg
• J9033 was: Injection, bendamustine hydrochloride, 1 mg
  now: Injection, bendamustine hydrochloride, not otherwise specified, 1 mg
• L1971 was: Ankle foot orthosis, plastic or other material with ankle joint, with or without dorsiflexion assist, prefabricated, includes fitting and adjustment
  now: Ankle foot orthosis, plastic or other material with ankle joint, with or without dorsiflexion assist, prefabricated, item that has been trimmed, bent, molded, assembled, or otherwise customized to fit a specific patient by an individual with expertise
• L8030 was: Breast prosthesis, silicone or equal, without integral adhesive
  now: Breast prosthesis, silicone or equal, without integral adhesive, any type
• L8031 was: Breast prosthesis, silicone or equal, with integral adhesive
  now: Breast prosthesis, silicone or equal, with integral adhesive, any type
• L8035 was: Custom breast prosthesis, post mastectomy, molded to patient model
  now: Custom breast prosthesis, post mastectomy, molded to patient model, any type
• S0169 was: Calcitrol, 0.25 microgram
  now: Calcitrol, oral, 0.25 microgram

Deleted codes — valid through September 30, 2026 (15)

• C8010 Percutaneous placement of permanent common carotid embolic protection device, including all system components and imaging guidance; bilateral
• C9046 Cocaine hydrochloride nasal solution (goprelto), 1 mg
• C9310 Injection, leucovorin calcium (avyxa), 1 mg
• C9462 Injection, delafloxacin, 1 mg
• J0640 Injection, leucovorin calcium, per 50 mg
• J1941 Injection, furosemide (furoscix), 20 mg
• J1953 Injection, levetiracetam, 10 mg
• J7514 Mycophenolate mofetil (myhibbin), oral suspension, 100 mg
• J7517 Mycophenolate mofetil, oral, 250 mg
• J7519 Injection, mycophenolate mofetil, 10 mg
• J7528 Mycophenolate mofetil, for suspension, oral, 100 mg
• J9181 Injection, etoposide, 10 mg
• J9190 Injection, fluorouracil, 500 mg
• J9352 Injection, trabectedin, 0.1 mg
• L8696 Antenna (external) for use with implantable diaphragmatic/phrenic nerve stimulation device, replacement, each

The new codes get their own pages here on October 1, 2026.